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Mounjaro is a branded weight loss medication (injection) containing Tirzepatide. It is prescribed to patients with a BMI over 27. The injectable medication is not suitable for everyone. Because of this there are natural alternatives to Mounjaro that can be purchased without prescription.

We’ll begin by taking a look at two natural weight loss supplements that are excellent OTC alternatives to Mounjaro. Then, we’ll take a look at the pros and cons of using the medication instead.

What are the Best Mounjaro Weight Loss Alternatives Available OTC?

Here are the two best over-the-counter alternatives to Mounjaro for body weight reduction:

• PhenQ (fat burner and appetite suppressant)
• Zotrim (herbal hunger craving reducer)

Zotrim could be seen as being the most fitting Mounjaro substitute because, like the medication, the only main weight loss benefit is appetite suppression.

There are several ways natural products can suppress appetite. One way is to slow gastric emptying. That’s what Zotrim does. Mounjaro does the same thing. That’s another reason why Zotrim could be seen as being the best Mounjaro OTC alternative.

However, although it does not suppress appetite using the same method, PhenQ is easily the top Mounjaro alternative because it provides such a superior level of overall weight management and loss support.

If all you want is a supplement that works like Mounjaro, choose Zotrim. If you want a diet pill that will get rid of your hunger and move your fat-burning machine into top gear, choose PhenQ instead.

PhenQ

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There is a good chance you have already heard about PhenQ. If not, where have you been? It’s the most talked about diet pill of the century and regularly appears at the top of all the “best diet pill” lists.

PhenQ has already helped 190,000+ people to lose weight and it continues to go from strength to strength. It has excellent customer reviews and a reputation as a weight loss provider that is second to none.

Do you know what else it has? A 60-day money-back guarantee. That means you can buy PhenQ and use it with absolutely nothing to lose.

However, we are not saying PhenQ is a magic weight-loss bullet. It’s not. Neither is Mounjaro or any other weight loss aid. It doesn’t matter which option you choose, you will need to commit to a low-calorie diet.

Keeping active will help as well by increasing your daily calorie expenditure but, if exercise is out of the question you can still lose or reduce body weight, with diet alone and PhenQ can help you to do it.

PhenQ Benefits

• Controls appetite and cravings
• Boosts energy
• Increases metabolism and fat burning
• Inhibits fat storage
• Enhances mood

PhenQ Ingredient Highlights

The PhenQ weight loss formulation contains seven science-backed natural ingredients including nopal cactus extract and cayenne pepper capsaicin.

PhenQ is also the only weight loss pill that provides a-Lacys Reset. 

Also known as prickly pear, nopal (Opuntia ficus) cactus assists weight loss by slowing carbohydrate digestion, food intake and absorption. Meanwhile, the amino acids it provides invigorate the body, helping to ward off diet-related fatigue.

Recent research conducted on obese women suggests nopal can also improve metabolism by causing favorable changes in the gut microbiota. [2]

Capsaicin is a plant compound that occurs naturally in capsicum peppers. Research shows capsaicin supports weight loss in multiple ways. It suppresses appetite, boosts metabolism to increase 24-hour energy expenditure, activates brown adipose tissue (BAT), and is helpful in other areas as well. [3]

Many people think a-Lacys Reset is the most important PhenQ ingredient. It’s not. They are all important but a-Lacys Reset tends to get extra attention because it’s still a relatively new ingredient.

a-Lacys Reset provides a patented blend of alpha-lipoic acid (ALA) and cysteine. ALA is an antioxidant. Cysteine is an amino acid. Put them together and they’re dynamite.

The participants in one study achieved 7.24% reductions in body fat accompanied by 3.8% increases in muscle mass. That’s very good.

Even acting alone. ALA has been shown to support modest improvements in reducing excess weight. [4]

Cysteine appears to act as a catalyst that enhances the overall fat-burning effect.

PhenQ Pros & Cons

Pros

• Provides ingredients that are proven effective for weight loss
• Supports weight loss in multiple ways
• Risk-free option with no known side effects
• Excellent customer reviews
• Cheaper than Mounjaro
• No needles or injections
• Sustainable weight loss
• Prevents future weight gain
• 60-Day Money-Back Guarantee

Cons

• Only available from the official website
• Sometimes sells out due to strong customer demand

Zotrim

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It may not be as versatile as PhenQ but Zotrim still functions well as a Mounjaro alternative because it works just like the medication.

Zotrim is a British diet pill. It’s been available for more than 20 years and, during that time, has built up an excellent reputation as a weight loss provider. It’s safe and effective and has the backing of a 100-day money-back guarantee.

As a Mounjaro alternative, Zotrim’s credentials are hard to beat. Its abilities are backed by five clinical trials and 10 expert-approved papers. Zotrim has also outperformed three major prescription drugs in clinical trials.

Although Zotrim works for men as well, it’s generally most popular with women and many of them state it helped them to go down a dress size within the first four weeks of treatment.

Zotrim Benefits

Zotrim is an appetite suppressant. That’s its sole function.

Zotrim Ingredient Highlights

Each Zotrim diet pill provides six natural ingredients. Guarana, yerba mate, and damiana are the three that have the greatest importance.

During our PhenQ ingredient evaluation, we pointed out the way cysteine enhances ALA’s weight loss capabilities. Guarana, yerba mate, and damiana share a similar synergy.

The results of a 45-day study conducted by researchers in Demark show this trio of herbs induced significant weight loss thanks to its ability to delay gastric emptying. [5]

Zotrim Pros & Cons

Pros

• Provides a combination of ingredients that has proven appetite-suppressing capabilities
• Boast impressive scientific credentials
• Decreased appetite, decrease food intake
• Has outperformed prescription drugs
• No needles or injections
• Cheaper for weight loss than Mounjaro
• The manufacturer offers a 100-day money-back guarantee

Cons

• The only benefit for reducing body weight is appetite suppression
• You can only buy it from the Zotrim website

What is Mounjaro

Mounjaro (Tirzepatide) is the latest medication to become an FDA-approved treatment for type-2 diabetes. As with similar antidiabetics, you have to take injectable medication for it just under the skin.

If you have heard Mounjaro is a new weight loss drug injection, that’s not strictly true. However, some doctors are using it as an off-label anti-obesity treatment.

The FDA allows doctors to prescribe drugs other than the way intended if doctors believe the treatment offers sufficient value to their patients.

Mounjaro has only been available since May 2022. However, its reputation as a weight loss aid has caused it to get a lot of attention. Especially on sites like TikTok.

One Mounjaro user on TikTok tracked her weight loss journey via regular updates and says the medication worked well alongside her diet and helped her to drop more weight 35 pounds during the first 11 weeks of treatment.

Research also suggests Mounaro can work for weight loss. The results of a 72-week clinical trial published in The New England Journal of Medicine show weekly injections enabled the obese study participants to obtain substantial reductions in total body weight alone. [1]

But let’s not forget, we are only talking about one study. If there were a dozen more that also supported using Mounjaro for weight loss, the medication would have greater credibility.

However, although there is a need for further investigation, Mounjaro shows a great deal of promise. Unfortunately, it has the potential to cause dangerous side effects so there are strong arguments for avoiding Moujaro and using an over-the-counter (OTC) alternative instead.

How Does Mounjaro Help You Lose Weight?

Mounjaro is the brand name for Tirzepatide. It’s a dual glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist).

All the other diabetes medications used for weight loss are only GLP-1 receptor agonists. The fact that Tirzepatide influences GIP as well makes it unique.

However, Mounjaro’s main value as a weight loss aid is due to it being a GLP-1 receptor agonist. Research shows drugs of this type delay gastric emptying sufficiently to reduce appetite. [6, 7]

How to Use Mounjaro for Weight Loss Medication

Mounjaro provides Tirzepatide in pre-dosed injector pens. You use each pen once and then throw it away.

Mounjaro injector pens are available in six strength options. New users generally begin with the lowest dose pen (2.5 mg) and then move up a size every month until they reach the maximum dose (15 mg).

Regardless of whether you are using Manjaro to manage type-2 diabetes or as an off-label weight aid, you only need to have one injection per week.

This is delivered under the skin, not into a muscle or vein. Although the thighs and upper arms are possible injection sites, most Mounjaro users find it easiest to take their injections in the stomach area.

“Mounjaro is primarily for blood sugar control and to combat insulin resistance. It was created to treat diabetes and glucose control. Tirzepatide has FDA approval for for diabetes but not weight reductions”

Who is Mounjaro Tirzepatide Suitable for

Mounjaro Tirzepatide, a groundbreaking medication specifically designed for the management of diabetes, has emerged as an effective solution for controlling blood sugar levels. 

Adapting to the needs of the modern world, Mounjaro is uniquely tailored for adults facing the challenges of obesity. 

Those with a body mass index (BMI) greater than 30, or even greater than 27 accompanied by an underlying obesity-related medical condition, can greatly benefit from this medication. 

Medical conditions that complement the use of Mounjaro include diabetes, high blood pressure, high cholesterol, and sleep apnea. 

By catering to individuals in these specific situations, Mounjaro Tirzepatide not only aids in achieving healthier blood sugar levels but also supports the journey to improve overall health and quality of life.

How to Obtain Mounjaro

The first thing you must do is make an appointment with your doctor or healthcare provider. They will ascertain whether you will be a suitable candidate for using Mounjaro for obesity management or losing weight.

How Much Does Mounjaro Cost?

Being a member of the incretin mimetics medication class, Mounjaro (tirzepatide) is frequently used for Type 2 Diabetes and Weight Loss (Obesity/Overweight). Depending on the pharmacy you go to, Mounjaro subcutaneous solution (2.5 mg/0.5 mL) costs about $1,087 for a supply of 2 ml.

Can I Get Mounjaro on Insurance Coverage

Some insurance companies cover Mounjaro – you will have to enquire from the company that provides you with medical insurance.

Other Similar Medications to Mounjaro

There are several other medications that are very similar to the Tirzepatide drug and positioned as treatment for obesity.

Semaglutide – sold under the brand names Wegovy and Ozempic, these are two similar diabetic jabs that are prescribed off label to help overweight men and women to reduce their BMI.

Mounjaro Side Effects and Dangers

The most common Mounjaro side effects are stomach-related:

• Indigestion
• Nausea
• Vomiting
• Stomach pain
• Constipation
• Diarrhea

Some Moujaro users also have problems with skin irritation around the injection site.

Although some people experience side effects such as these, others do not. Responses vary on an individual level. The same is true for all prescription medications.

Unfortunately, GLP-1 receptor agonists also present more serious health concerns. The Mounjaro website makes this clear by displaying a prominent warning that states the medication has the potential to cause thyroid cancer. The package insert distributed with Mounjaro provides the same information.

Gallbladder problems, pancreatitis, and kidney failure are further potential Mounjaro side effects.

The link between GLP-1 receptor agonists and thyroid cancer has been a controversial topic for a long time and recent research, published in Diabetes Care in 2021, has a worrying conclusion:

“In the current study, we found an increased risk of all thyroid cancer and medullary thyroid cancer with the use of GLP-1 RA, in particular after 1–3 years of treatment.” [8]

Mounjaro Tirzepatide for Weight Loss: Is It Worth It?

Thyroid cancer! It’s hard to imagine a side effect more severe than that. Some of the other potential Mounjaro side effects are pretty unnerving too. It seems crazy that some people are willing to take such risks just to lose weight.

Is it worth taking a gamble on average weight loss by using this drug? We don’t think so but you are free to formulate your own opinion about that. The information this article provides should help you to do it but if you are still keen to start sticking needles into your stomach, please bear in mind the level of weight loss support Mounjaro provides is very limited. It only suppresses appetite.

Zotrim can do this too. It even works in the same way as Mounjaro but does not present any of the risks. PhenQ suppresses appetite too and offers many additional benefits. For our money, it’s easily the best over the counter alternative to Mounjaro.

Sticking with the subject of money, we should also point out Mounjaro is a very expensive medication. A four-week treatment generally costs upwards of $1100. That’s not going to cause financial hardship if your insurance company is willing to pick up the bill but the chances of this are slim.

By comparison, using Zotrim will only cost you $50 per month. PhenQ is only $20 more and, in both cases, it’s possible to get even greater value for money by taking advantage of special offers that allow you to get three bottles/packets for the price of two or five for the price of three.

Mounjaro Tirzepatide Injection Pros and Cons

Pros

• Can be effective for appetite suppression and weight loss
• Only requires one treatment per week

Cons

• Not a good option for people who don’t like needles
• Not FDA approved for weight loss 
• Can cause dangerous side effects
• Expensive way to lose weight

Mounjaro Tirzepatide Research Sources and Clinical Trials 2023

1. Tirzepatide Once Weekly for the Treatment of Obesity: https://www.nejm.org/doi/full/10.1056/NEJMoa2206038
2. Physical and Dietary Intervention with Opuntia ficus-indica (Nopal) in Women with Obesity Improves Health Condition through Gut Microbiota Adjustment: https://pubmed.ncbi.nlm.nih.gov/35267983/
3. Dietary Capsaicin and Its Anti-obesity Potency: From Mechanism to Clinical Implications: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426284/
4. Alpha-Lipoic Acid (Ala) As a Supplementation for Weight Loss: Results From a Meta-Analysis of Randomized Controlled Trials: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523816/
5. Weight Loss and Delayed Gastric Emptying Following a South American Herbal Preparation in Overweight Patients: https://pubmed.ncbi.nlm.nih.gov/11424516/
6. Therapy in the Early Stage: Incretins: https://pubmed.ncbi.nlm.nih.gov/21525466/
7. Glucagon-Like Peptide 1 Promotes Satiety and Suppresses Energy Intake in Humans: https://pubmed.ncbi.nlm.nih.gov/9449682/
8. GLP-1 Receptor Agonists and the Risk of Thyroid Cancer: https://diabetesjournals.org/care/article-abstract/46/2/384/147888/GLP-1-Receptor-Agonists-and-the-Risk-of-Thyroid?redirectedFrom=fulltext
9. Diabetes drugs for weight loss: https://www.outlookindia.com/outlook-spotlight/best-diabetes-drug-for-weight-loss-which-diabetes-medication-is-best-to-lose-weight-news-247860